What Does Cialis Do?

When it was introduced in 2003, Cialis was considered a “blockbuster” drug for the company that created it, Lilly USA, thanks to the $1.1 billion it has earned per year since then. The past few years have seen Cialis rise to be the second most popular ED drug behind only Viagra.

While Cialis is within the same drug class as the other prescription drugs for ED that are popular like Staxyn, Viagra, and Levitra, the way it’s formulated is different enough to provide unique effects.

The Condition Cialis Treats

When men experience sexual arousal, they experience an increase in blood flow to their penis, resulting in an erection. The blood flows thanks to the relaxation of the penile arteries in the smooth muscle in the penis, named the corpus cavernosum. The arteries relax when nitric oxide is released from nerve endings, creating a compound known as cGMP, or cyclic nucleotide guanosine monophosphate, which relaxes muscles and increases the flow of blood.

When any part of this process doesn’t occur, it results in erectile dysfunction. What stops this process is not clear. Sexual arousal in men is a complex process that involves more than just nerves, blood vessels, and muscles. It also involves emotions, the brain, and hormones. ED can be caused by an issue with any of these components. Problems with mental health and an increase in stress can also contribute or worsen ED.

How Cialis Works

When you take Cialis, it stops an important enzyme called PDE5, or phosphodiesterase type 5. When the body has less PDE5, it allows for more cGMP which means there’s more of a chance of achieving an erection. Taking Cialis doesn’t mean that the user will immediately get an erection because the release of nitric oxide only occurs with sexual stimulation.

Cialis isn’t just used to treat ED. For men and women who suffer from pulmonary hypertension or PAH, blood vessels located inside their lungs are constricted in their size. This causes their blood pressure to be abnormally high. PAH can cause heart failure in the worse scenario. Cialis’s main ingredient Tadalafil does the same thing it does to the smooth muscles in the penis to the walls of the lung. It relaxes the arteries, allowing blood vessels to open and lowering the high blood pressure.

How It Compares to Other Drugs

Unlike other drugs that fall into the same class, Cialis lasts much longer. Other drugs are effective for only four to six hours; Cialis can work for up to 36 hours. Cialis is also a lot more effective when it comes to limiting PDE5 levels without causing a change in enzyme levels of PDE7, PDE4, PDE2, and PDE1. These other enzymes are found in the skeleton, liver, brain, and blood vessels.

It is also thought to provide some relief to men who suffer from benign prostatic hyperplasia, commonly known as BPH. It’s unclear on how it works, but it’s thought that it does the same thing it does with the other conditions it treats. It relaxes the muscles of the bladder and prostate, improving blood flow.

To put simply, Cialis results in the relaxation of arteries which can help men achieve erections or women and men with PAH to get more blood flow. When it comes to effectiveness, it’s four times as effective as other drugs that help with ED.

About Benjamin AbramovDr Benjamin Abramov is a leading fertility specialist and gynaecologist based in London, and is currently Medical Director of City Fertility Ltd. Specialising in pre-implantation genetic screening (PGS) and pre-implantation genetic diagnosis (PGD), IVF, and the management of recurrent miscarriages, Dr Abramov's ethos is a patient-centred approach, tailoring treatment to each individual case, and putting the needs of his patients first.Benjamin Abramov Facebook Benjamin Abramov Google Plus Benjamin Abramov Twitter Benjamin Abramov Medium Benjamin Abramov Wordpress Benjamin Abramov Blogger