Cialis Ingredients

Cialis is a brand name medicine for tadalafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP). The empirical formula for tadalafil is C22H19N3O4, which represents a molecular weight of 389.41. It’s a crystalline solid that is slightly soluble in ethanol and basically insoluble in water.

Cialis can be found in an almond-shaped tablet for oral consumption. Each tablet can contain 2.5, 5, 10, or 20 mg of tadalafil plus other inactive ingredients. These inactive ingredients include croscarmellose sodium, hydroxypropyl cellulose, iron oxide, triacetin, sodium lauryl sulfate, titanium dioxide, talc, lactose monohydrate, hypromellose, microcrystalline cellulose, and magnesium stearate.

Tadalafil

While ED medication, whether it’s tadalafil, sildenafil, or vardenafil, all work by inhibiting PDE5, tadalafil has a pharmacological distinction that sets it apart: it’s longer half-life. The longer half-life results in a longer duration for effectiveness. The longer half-life is also what makes the compound effective for helping daily with other conditions such as pulmonary arterial hypertension.

The recommended starting dose of tadalafil for the majority of men is 10 mg. It’s normally taken as needed before someone engages in sexual activity, but not more than once per day. The dose can increase to 20 mg when needed or decrease to 5 mg. It all depends on a man’s personal tolerance and the efficacy of the drug. A low dose of 5 mg, or even 2.5 mg, can be taken once daily for ED therapy.

For patients suffering from pulmonary arterial hypertension, tadalafil has been approved for 40 mg per day for therapy. It helps improve patients’ ability to exercise. In patients that have PAH, there is a decrease in the pulmonary vascular lumen as a result of vascular remodeling and vasoconstriction. This results in an increase of pulmonary vascular resistance and pulmonary artery pressure. The use of tadalafil is believed to inhibit vascular remodeling and increase pulmonary artery vasodilation, which would lower pulmonary vascular resistance and pulmonary arterial pressure. If pulmonary arterial hypertension isn’t treated then it can result in heart failure.

Croscarmellose Sodium

Croscarmellose sodium is used as a super disintegrant in the formulations of pharmaceutical drugs and is cross-linked internally with sodium carboxymethylcellulose. The cross-linking allows for a reduction in water solubility. It allows whatever it’s in to swell like a sponge and absorb its weight in water many times over. This ability provides superior characteristics in drug disintegration and drug dissolution. It improves the formulas’ bioavailability by bringing whatever active ingredients available into better contact with the bodily fluids.

Hydroxypropyl Cellulose

Hydroxypropyl cellulose is another ingredient that helps with water solubility and also organic solubility. It’s usually used as an excipient. It can be used as a topical oPAHhalmic lubricant and protectant.

The Other Ingredients

The other ingredients present in Cialis are similar to croscarmellose sodium and hydroxypropyl cellulose; they make up the physical and chemical structure of the pill itself. They work together to form all the physical characteristics of the pill and allow for tadalafil to be properly and effectively absorbed in your system. These ingredients, while they affect the pill itself, don’t have any effect on the users who take the pill which is why they’re known as inactive ingredients.

Possible Side Effects

If you have an allergic reaction to tadalafil, you should get emergency medical help. While rare, it is possible to have an allergic reaction to the inactive ingredients in a product, but it’s usually the active ingredients. This type of reaction can include swelling in your throat or on your tongue, face, or lips; swelling; and hives.

You should also seek medical help if you experience dizziness, chest pain, or nausea during sexual intercourse. This could be a symptom of a life-threatening side effect.

Other signs that you may need medical attention include a feeling of lightheadedness (or a feeling like you might pass out), an erection that lasts more than 4 hours (which can cause severe damage to the penis), an erection that is painful, sudden vision loss or changes in your vision, ringing in your ears, sudden hearing loss, or any symptoms related to heart attacks (chest pressure or pain, pain that spreads to your shoulder or jaw, sweating, and nausea). If you notice any of these symptoms, contact your doctor immediately.

About Benjamin AbramovDr Benjamin Abramov is a leading fertility specialist and gynaecologist based in London, and is currently Medical Director of City Fertility Ltd. Specialising in pre-implantation genetic screening (PGS) and pre-implantation genetic diagnosis (PGD), IVF, and the management of recurrent miscarriages, Dr Abramov's ethos is a patient-centred approach, tailoring treatment to each individual case, and putting the needs of his patients first.Benjamin Abramov Facebook Benjamin Abramov Google Plus Benjamin Abramov Twitter Benjamin Abramov Medium Benjamin Abramov Wordpress Benjamin Abramov Blogger